Chia-Hung Chen Selected Research

Oncogene Addiction

1/2018	Cigarette smoke enhances oncogene addiction to c-MET and desensitizes EGFR-expressing non-small cell lung cancer to EGFR TKIs.
1/2018	Incense burning smoke sensitizes lung cancer cells to EGFR TKI by inducing AREG expression.
11/2013	Lapatinib-induced NF-kappaB activation sensitizes triple-negative breast cancer cells to proteasome inhibitors.

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Chia-Hung Chen Research Topics

Disease

30	Neoplasms (Cancer) 01/2022 - 11/2010
10	Breast Neoplasms (Breast Cancer) 10/2021 - 01/2013
9	Lung Neoplasms (Lung Cancer) 01/2022 - 05/2014
8	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 05/2022 - 01/2018
8	Infections 01/2022 - 08/2007
8	Chronic Obstructive Pulmonary Disease (COPD) 10/2021 - 01/2014
7	Neoplasm Metastasis (Metastasis) 05/2022 - 04/2015
6	Asthma (Bronchial Asthma) 01/2021 - 01/2015
3	Pneumonia (Pneumonitis) 01/2022 - 03/2010
3	Triple Negative Breast Neoplasms 01/2020 - 11/2013
3	Disease Progression 01/2019 - 04/2015
3	Oncogene Addiction 01/2018 - 11/2013
3	Pleural Effusion (Pleural Effusions) 01/2018 - 02/2009
2	Ventilator-Associated Pneumonia 01/2022 - 01/2021
2	Brain Neoplasms (Brain Tumor) 01/2022 - 09/2020
2	Healthcare-Associated Pneumonia 01/2022 - 01/2021
2	Wounds and Injuries (Trauma) 01/2021 - 10/2010
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 09/2014
2	Shock 01/2021 - 04/2019
2	Pathologic Constriction (Stenosis) 01/2021 - 09/2019
2	Communicable Diseases (Infectious Diseases) 11/2020 - 01/2012
2	Leukemia 11/2019 - 07/2016
2	Critical Illness (Critically Ill) 04/2019 - 02/2009
2	Respiratory Insufficiency (Respiratory Failure) 04/2019 - 04/2008
2	Acute Kidney Injury (Acute Renal Failure) 04/2019 - 04/2008
2	Endometriosis 05/2013 - 02/2013
2	End Stage Liver Disease 07/2012 - 03/2011
2	Abscess 02/2012 - 06/2005
2	Fever (Fevers) 02/2012 - 06/2005
2	Pneumothorax 01/2012 - 11/2006
2	Empyema 09/2009 - 08/2007
1	Lactic Acidosis 01/2022
1	COVID-19 01/2021
1	Cerebral Hemorrhage 01/2021
1	Coronavirus Infections 01/2021
1	Heart Arrest (Cardiac Arrest) 01/2021
1	Eosinophilia 01/2021
1	Severe Acute Respiratory Syndrome 01/2021
1	Aortic Dissection 01/2021
1	Anaphylaxis (Anaphylactic Shock) 01/2021
1	Prostatic Neoplasms (Prostate Cancer) 01/2021

Drug/Important Bio-Agent (IBA)

11	Tyrosine Kinase InhibitorsIBA 05/2022 - 01/2013
10	Pharmaceutical PreparationsIBA 05/2022 - 04/2012
9	ErbB Receptors (EGF Receptor)IBA 05/2022 - 11/2013
7	Proteins (Proteins, Gene)FDA Link 04/2020 - 11/2010
6	Anti-Bacterial Agents (Antibiotics)IBA 01/2017 - 06/2005
5	Biomarkers (Surrogate Marker)IBA 12/2021 - 09/2014
5	Peptide Hydrolases (Proteases)FDA Link 01/2019 - 02/2013
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020 - 11/2010
4	SmokeIBA 12/2019 - 01/2014
3	Lapatinib (GW572016)FDA Link 10/2021 - 11/2013
3	Interleukin-8 (Interleukin 8)IBA 01/2021 - 03/2010
3	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2017
3	Biological ProductsIBA 01/2021 - 01/2020
2	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2022 - 05/2018
2	Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric 01/2022 - 01/2021
2	AfatinibIBA 01/2022 - 05/2018
2	Cefoperazone (Cefoperazone Sodium)FDA Link 01/2022 - 01/2021
2	Sulbactam FDA LinkGeneric 01/2022 - 01/2021
2	Small Interfering RNA (siRNA)IBA 12/2021 - 01/2014
2	DNA (Deoxyribonucleic Acid)IBA 12/2021 - 11/2008
2	human ERBB2 proteinIBA 10/2021 - 11/2013
2	Interleukin-6 (Interleukin 6)IBA 01/2021 - 03/2010
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 03/2010
2	poly(ethylene glycol)-co-poly(ethyleneimine)IBA 04/2020 - 02/2019
2	Muscarinic AntagonistsIBA 01/2020 - 06/2018
2	Tiotropium Bromide (Spiriva)FDA Link 09/2019 - 06/2018
2	Adrenal Cortex Hormones (Corticosteroids)IBA 06/2018 - 11/2015
2	Metalloproteases (Metalloproteinases)IBA 07/2016 - 02/2015
2	Estrogen ReceptorsIBA 02/2016 - 11/2013
2	Matrix Metalloproteinases (MMPs)IBA 04/2015 - 02/2015
2	tyrosine receptor (receptor, tyrosine)IBA 05/2014 - 01/2013
2	Phosphotransferases (Kinase)IBA 05/2014 - 01/2013
2	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 05/2011 - 11/2010
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2022
1	AntibodiesIBA 01/2022
1	osimertinibIBA 01/2022
1	Protein Kinase CIBA 01/2022
1	HydrogelsIBA 12/2021
1	GoldIBA 10/2021
1	Peptides (Polypeptides)IBA 01/2021
1	Bronchodilator Agents (Bronchodilators)IBA 01/2021
1	Potassium Channels (Potassium Channel)IBA 01/2021
1	camostatIBA 01/2021
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2021
1	flupirtineIBA 01/2021
1	nafamostatIBA 01/2021
1	Environmental BiomarkersIBA 01/2021
1	Serine Proteases (Serine Protease)IBA 01/2021

Therapy/Procedure

24	Therapeutics 01/2022 - 06/2005
5	Catheters 01/2012 - 08/2007
3	Radiotherapy 01/2022 - 09/2020
2	Drug Therapy (Chemotherapy) 05/2022 - 05/2018
2	Precision Medicine 12/2021 - 01/2019
2	Self Expandable Metallic Stents 09/2019 - 05/2018
2	Critical Care (Surgical Intensive Care) 04/2019 - 04/2008
2	Length of Stay 01/2012 - 11/2006
1	Stents 01/2021
1	Secondary Prevention 01/2021
1	Conservative Treatment 01/2021